Associazione PNEI - O.D.V.

Research, Education and Integrated Care in Clinical Psychoneuroendocrinoimmunology

A scientific approach uniting mind, endocrine system and immune system for a new vision of health

The Honorary President

Prof. Paolo Lissoni

Prof. Paolo Lissoni, born in Milan in spring 1954, is an Italian oncologist and endocrinologist internationally recognized for his pioneering research on the pineal gland and its role in cancer treatment.

Academic Background:

  • MD in Medicine & Surgery (1979, with honors)
  • Specialist in Endocrinology (1982)
  • Specialist in Medical Oncology (1988)
  • Specialist in Internal Medicine (1993)
  • Degree in Theology (2010)

He received an award from the Washington National Cancer Institute for his pioneering research on the pineal gland. His unique approach integrates medicine and spirituality, laying the foundation for a new biopsychosocial vision of oncological care.

Board

Monzon Cortarelli Alejandra Victoria

President

Coordinates the association's activities and represents its institutional vision.

Gaetani Alessandra

Vice President

Supports the presidency and coordinates research and training projects.

Valentini Agnese

Treasurer

Manages the association's financial resources and planning.

Clinical PNEI

Psychoneuroendocrinoimmunology (PNEI) is a scientific discipline that studies the interconnections between the nervous system, endocrine system, and immune system, demonstrating how mind and body are deeply connected through the chemical mediation of emotions and states of consciousness.

PNEI represents an integrated approach that recognizes the fundamental relationship between the endocrine, nervous, and immune systems. These three systems communicate constantly through signaling molecules (hormones, neurotransmitters, cytokines), creating a complex network of interconnections that regulates health and disease.

The integration of endocrinology, neuropsychiatry, and immunology is essential for understanding how psychological stress, emotions, and mental states directly influence immune function and disease progression. This paradigm transcends the reductionist view of conventional medicine.

Clinical PNEI, developed by Prof. Lissoni, represents the clinical application of these scientific principles to medical practice, particularly in oncology. This approach considers the patient in their totality - biological, psychological, and social - promoting therapies that modulate neuroendocrine-immune balance.

The Clinical PNEI association promotes research, education, and dissemination of this integrated approach to care, with particular attention to the role of melatonin and other endogenous molecules in maintaining health and modulating the antitumor response.

Who We Serve

The PNEI Association addresses a broad and diverse audience of professionals and enthusiasts who wish to deepen their understanding of the connection between mind, body, and spirit:

  • Physicians - Oncologists, endocrinologists, internists, and specialists who wish to integrate the PNEI approach into their clinical practice
  • Researchers - Scientists interested in exploring the mechanisms of interconnection between biological systems
  • Healthcare Professionals - Nurses, physiotherapists, and other health professionals who want to expand their holistic vision of the patient
  • Psychologists and Psychotherapists - Mental health professionals who recognize the importance of the biological dimension in psychological disorders
  • Epigeneticists - Researchers interested in how environment and emotions influence gene expression
  • Quantum Physicists - Scientists exploring the quantum foundations of biology and consciousness
  • Philosophers - Thinkers interested in the philosophical implications of mind-body-spirit integration
  • Anyone Concerned with Human Beings - Educators, coaches, counselors, and all those who wish to understand human nature more deeply

Those who ask a question find a path toward the answer. The PNEI Association offers a space for research, education, and sharing for those seeking a deeper and more integrated understanding of human health, recognizing that every question is an invitation to discover new dimensions of knowledge.

Research Areas

Pineal Gland

Study of pineal gland (epiphysis) functions and its role in regulating biological rhythms and immune response. Prof. Lissoni's research has highlighted the importance of this organ in modulating tumor growth.

Melatonin

Research on the antioxidant, immunomodulatory, and oncostatic properties of melatonin. Clinical studies have demonstrated beneficial effects on the quality of life of cancer patients and in enhancing conventional therapies.

Cytokine Regulation

Analysis of the cytokine network (IL-2, IL-12, TNF) and their balance in the antitumor response. The PNEI approach aims to restore the cytokine balance altered in neoplastic diseases.

Events

The PNEI Association regularly organizes conferences, seminars, training courses, and scientific meetings dedicated to Clinical Psychoneuroendocrinoimmunology. Events are designed for physicians, researchers, healthcare professionals, and practitioners interested in deepening their understanding of this integrated approach.

The events calendar will be published soon. Stay updated to discover upcoming training and networking opportunities.

Calendar Updating

New events are being scheduled. Check back regularly to discover conferences, seminars, and training courses on Clinical PNEI.

Conferences & Seminars

Scientific meetings with international experts on Psychoneuroendocrinoimmunology, melatonin, pineal gland, and clinical applications in oncology.

Training Courses

Structured educational programs for healthcare professionals who wish to acquire advanced skills in the PNEI approach and neuroimmunomodulation.

Publications

Prof. Paolo Lissoni is the author of over 700 peer-reviewed scientific publications indexed on PubMed and more than 33 books on PNEI and oncology.

His research has been published in high-impact international journals and has helped define the field of neuroimmunomodulation in oncology.

View on PubMed →

Affiliations

  • IIPNE International Institute of Psychoneuroendocrinology
  • San Gerardo Hospital Monza, Italy - Oncology Division
  • Institute of Biological Medicine Milan, Italy

Contact

Associazione PNEI - O.D.V.

For information about the association and educational activities:

Email: info@clinicalpnei.com

Become a Member

Join the PNEI Association to access exclusive resources, continuous education, and a community of professionals dedicated to Clinical Psychoneuroendocrinoimmunology.